منابع مشابه
Lamellar keratoplasty with lyophilized tissue for treatment of corneal scarring.
BACKGROUND A pilot study was carried out in Pakistan to assess the feasibility of the use of lathed freeze-dried corneal tissue in the treatment of corneal scarring. METHOD Six eyes underwent lamellar keratoplasty and were followed up for 18 months. RESULTS Visual improvement was obtained in every eye. In one eye, the procedure was complicated by delayed epithelialization of the graft, but ...
متن کاملmRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration
Duchenne muscular dystrophy (DMD) is a pediatric, X-linked, progressive muscle-wasting disorder caused by loss of function mutations affecting the gene encoding the dystrophin protein. While the primary genetic insult in DMD is well described, many details of the molecular and cellular pathologies that follow dystrophin loss are incompletely understood. To investigate gene expression in dystrop...
متن کاملTumor immunity in mice, induced with lyophilized tissue, as influenced by tumor strain, host strain, source of tissue, and dosage.
When tumors originating in one inbred strain of mice are transplanted into a second inbred strain (homoiotransplants) they usually show either no growth, or temporary growth followed by complete regression. The maximum size attained varies greatly according to the tumor and host strain employed, but for any one combination of tumor and host strain it is often quite uniform. Particularly is this...
متن کاملComparison of Protamine 1 to Protamine 2 mRNA Ratio and YBX2 gene mRNA Content in Testicular Tissue of Fertile and Azoospermic Men
Background Although aberrant protamine (PRM) ratios have been observed in infertile men, the mechanisms that implicit the uncoupling of PRM1 and PRM2 expression remain unclear. To uncover these mechanisms, in this observational study we have compared the PRM1/PRM2 mRNA ratio and mRNA contents of two regulatory factors of these genes. MaterialsAndMethods In this experimental study, sampling was ...
متن کاملExon skipping during splicing of dystrophin mRNA precursor due to an intraexon deletion in the dystrophin gene of Duchenne muscular dystrophy kobe.
Recent molecular studies have shown that in a patient with Duchenne muscular dystrophy (DMD) Kobe, the size of exon 19 of the dystrophin gene was reduced to 36 bp due to the deletion of 52 bp out of 88 bp of the exon. The consensus sequences at the 5' and 3' splice sites of exon 19 were unaltered (Matsuo, M., et al. 1990. Biochem. Biophys. Res. Commun. 170:963-967). To further elucidate the mol...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature
سال: 1992
ISSN: 0028-0836,1476-4687
DOI: 10.1038/355778a0